Regulation of apoptosis in nucleus pulposus cells by optimized exogenous Bcl-2 overexpression
نویسندگان
چکیده
منابع مشابه
Integrin β1 overexpression protects nucleus pulposus cells from apoptosis and attenuates intervertebral disc degeneration
Intervertebral disc (IVD) degeneration is a chronic pathologic process characterized by excessive apoptosis of intervertebral disc cells. The purpose of the current study was to detect the effect of integrin β1 on apoptosis of NP cells and IVD degeneration. Integrin β1 overexpressing lentivirus vector (LV-ITG β1) was constructed and transduced to NP cells, and its effect on cell apoptosis were ...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research
سال: 2010
ISSN: 0736-0266
DOI: 10.1002/jor.21185